Two factor authentication: Asf1 mediates crosstalk between H3 K14 and K56 acetylation

The ability of histone chaperone Anti-silencing factor 1 (Asf1) to direct acetylation of lysine 56 of histone H3 (H3K56ac) represents an important regulatory step in genome replication and DNA repair. In Saccharomyces cerevisiae, Asf1 interacts functionally with a second chaperone, Vps75, and the ly...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Cote, Joy M, Kuo, Yin-Ming, Henry, Ryan A, Scherman, Hataichanok, Krzizike, Daniel D, Andrews, Andrew J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698667/
https://ncbi.nlm.nih.gov/pubmed/31194870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz508
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