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hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles

Alternative cleavage and polyadenylation (APA) can occur at more than half of all human genes, greatly enhancing the cellular repertoire of mRNA isoforms. As these isoforms can have altered stability, localisation and coding potential, deregulation of APA can disrupt gene expression and this has bee...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Fischl, Harry, Neve, Jonathan, Wang, Zhiqiao, Patel, Radhika, Louey, Alastair, Tian, Bin, Furger, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698646/
https://ncbi.nlm.nih.gov/pubmed/31147722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz461
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