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hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles

Alternative cleavage and polyadenylation (APA) can occur at more than half of all human genes, greatly enhancing the cellular repertoire of mRNA isoforms. As these isoforms can have altered stability, localisation and coding potential, deregulation of APA can disrupt gene expression and this has bee...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Fischl, Harry, Neve, Jonathan, Wang, Zhiqiao, Patel, Radhika, Louey, Alastair, Tian, Bin, Furger, Andre
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698646/
https://ncbi.nlm.nih.gov/pubmed/31147722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz461
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