Tumor Necrosis Factor-α Produced by Osteoclasts Might Induce Intractable Pain in a Rat Spinal Metastasis Model of Breast Cancer

INTRODUCTION: Causes of pain due to spinal metastases have been insufficiently investigated. Tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) were the focus of this study. Both are known as proinflammatory cytokines associated with the pathophysiology of pain syndromes(1)()). It is well know...

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Publicat a:Spine Surg Relat Res
Autors principals: Mazaki, Ai, Orita, Sumihisa, Inage, Kazuhide, Suzuki, Miyako, Abe, Kohki, Shiga, Yasuhiro, Inoue, Masahiro, Norimoto, Masaki, Umimura, Tomotaka, Ohtori, Seiji, Yamauchi, Kazuyo
Format: Artigo
Idioma:Inglês
Publicat: The Japanese Society for Spine Surgery and Related Research 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698511/
https://ncbi.nlm.nih.gov/pubmed/31440686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22603/ssrr.2018-0106
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