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Amino Acid Biosynthesis Regulation during Endoplasmic Reticulum Stress Is Coupled to Protein Expression Demands

The endoplasmic reticulum (ER) stress response, also known as the unfolded protein response (UPR), is a complex cellular response to ER protein misfolding that involves transcriptional regulatory branches and a PERK-mediated translational regulatory branch. Here we revealed that amino acid biosynthe...

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Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Gonen, Nir, Meller, Anatoly, Sabath, Niv, Shalgi, Reut
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698312/
https://ncbi.nlm.nih.gov/pubmed/31377665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.07.022
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