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Targeting transcriptional machinery to inhibit enhancer-driven gene expression in heart failure

Pathological cardiac remodeling is induced through multiple mechanisms that include neurohumoral and biomechanical stress resulting in transcriptional alterations that ultimately become maladaptive and lead to the development of heart failure (HF). Although cardiac transcriptional remodeling is medi...

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Vydáno v:Heart Fail Rev
Hlavní autoři: Minerath, Rachel A., Hall, Duane D., Grueter, Chad E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698214/
https://ncbi.nlm.nih.gov/pubmed/30972522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10741-019-09792-3
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