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Ni-Catalyzed Carbon-Carbon Bond-Forming Reductive Amination

This report describes a three-component, Ni-catalyzed reductive coupling that enables the convergent synthesis of tertiary benzhydryl amines, which are challenging to access by traditional reductive amination methodologies. The reaction makes use of minium ions generated in situ from the condensatio...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Heinz, Christoph, Lutz, J. Patrick, Simmons, Eric M., Miller, Michael M., Ewing, William R., Doyle, Abigail G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698183/
https://ncbi.nlm.nih.gov/pubmed/29341599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12212
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