Dynamic colocalization of 2 simultaneously active VSG expression sites within a single expression-site body in Trypanosoma brucei

Monoallelic exclusion ensures that the African trypanosome Trypanosoma brucei exclusively expresses only 1 of thousands of different variant surface glycoprotein (VSG) coat genes. The active VSG is transcribed from 1 of 15 polycistronic bloodstream-form VSG expression sites (ESs), which are controll...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Budzak, James, Kerry, Louise E., Aristodemou, Aris, Hall, Belinda S., Witmer, Kathrin, Kushwaha, Manish, Davies, Carys, Povelones, Megan L., McDonald, Jacquelyn R., Sur, Aakash, Myler, Peter J., Rudenko, Gloria
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697882/
https://ncbi.nlm.nih.gov/pubmed/31358644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905552116
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