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FACT plays a major role in histone dynamics affecting VSG expression site control in Trypanosoma brucei

Chromatin remodelling is involved in the transcriptional regulation of the RNA polymerase I transcribed variant surface glycoprotein (VSG) expression sites (ESs) of Trypanosoma brucei. We show that the T. brucei FACT complex contains the Pob3 and Spt16 subunits, and plays a key role in ES silencing....

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Bibliografiske detaljer
Udgivet i:Mol Microbiol
Main Authors: Denninger, Viola, Rudenko, Gloria
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625058/
https://ncbi.nlm.nih.gov/pubmed/25266856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12812
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