Mechanical and kinetic factors drive sorting of F-actin cross-linkers on bundles

In cells, actin-binding proteins (ABPs) sort to different regions to establish F-actin networks with diverse functions, including filopodia used for cell migration and contractile rings required for cell division. Recent experimental work uncovered a competition-based mechanism that may facilitate s...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Freedman, Simon L., Suarez, Cristian, Winkelman, Jonathan D., Kovar, David R., Voth, Gregory A., Dinner, Aaron R., Hocky, Glen M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697872/
https://ncbi.nlm.nih.gov/pubmed/31346091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820814116
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