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In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating

Bluetongue virus (BTV), a major threat to livestock, is a multilayered, nonturreted member of the Reoviridae, a family of segmented dsRNA viruses characterized by endogenous RNA transcription through an RNA-dependent RNA polymerase (RdRp). To date, the structure of BTV RdRp has been unknown, limitin...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: He, Yao, Shivakoti, Sakar, Ding, Ke, Cui, Yanxiang, Roy, Polly, Zhou, Z. Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697807/
https://ncbi.nlm.nih.gov/pubmed/31350350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905849116
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