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In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release
Transcribing and replicating a double-stranded genome require protein modules to unwind, transcribe/replicate nucleic acid substrates, and release products. Here we present in situ cryo-electron microscopy structures of rotavirus dsRNA-dependent RNA polymerase (RdRp) in two states pertaining to tran...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6525196/ https://ncbi.nlm.nih.gov/pubmed/31101900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10236-7 |
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