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Heterogeneous Loop Model to Infer 3D Chromosome Structures from Hi-C
Adapting a well-established formalism in polymer physics, we develop a minimalist approach to infer three-dimensional folding of chromatin from Hi-C data. The three-dimensional chromosome structures generated from our heterogeneous loop model (HLM) are used to visualize chromosome organizations that...
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| Publicado no: | Biophys J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697451/ https://ncbi.nlm.nih.gov/pubmed/31337548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.06.032 |
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