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SCL: a lattice-based approach to infer 3D chromosome structures from single-cell Hi-C data

MOTIVATION: In contrast to population-based Hi-C data, single-cell Hi-C data are zero-inflated and do not indicate the frequency of proximate DNA segments. There are a limited number of computational tools that can model the 3D structures of chromosomes based on single-cell Hi-C data. RESULTS: We de...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Zhu, Hao, Wang, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792089/
https://ncbi.nlm.nih.gov/pubmed/30865261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz181
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