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Endogenous AT1 Receptor–Protein Kinase C Activity in the Hypothalamus Augments Glutamatergic Input and Sympathetic Outflow in Hypertension
Increased synaptic N-methyl-D-aspartate receptor (NMDAR) activity in the hypothalamic paraventricular nucleus (PVN) plays a major role in elevated sympathetic output in hypertension. Although exogenous angiotensin II (AngII) can increase NMDAR activity in the PVN, whether endogenous AT1 receptor–pro...
Enregistré dans:
| Publié dans: | J Physiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697190/ https://ncbi.nlm.nih.gov/pubmed/31241170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP278427 |
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