A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice

Skeletal muscle cell (myofiber) atrophy is a detrimental component of aging and cancer that primarily results from muscle protein degradation via the proteasome and ubiquitin ligases. Transcriptional upregulation of some ubiquitin ligases contributes to myofiber atrophy, but little is known about th...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Hunt, Liam C., Stover, Jared, Haugen, Benard, Shaw, Timothy I., Li, Yuxin, Pagala, Vishwajeeth R., Finkelstein, David, Barton, Elisabeth R., Fan, Yiping, Labelle, Myriam, Peng, Junmin, Demontis, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697171/
https://ncbi.nlm.nih.gov/pubmed/31365869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.094
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