Cytokine regulated phosphorylation and activation of TET2 by JAK2 in hematopoiesis

Even though the TET enzymes catalyze the generation of 5-hydroxymethyl-cytosines required for lineage commitment and subsequent differentiation of stem cells into erythroid cells, the mechanisms that link extra-cellular signals to TET activation and DNA hydroxymethylation are unknown. We demonstrate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Jeong, Jong Jin, Gu, Xiaorong, Nie, Ji, Sundaravel, Sriram, Liu, Hui, Kuo, Wen-Liang, Bhagat, Tushar D, Pradhan, Kith, Cao, John, Nischal, Sangeeta, McGraw, Kathy L., Bhattacharyya, Sanchari, Bishop, Michael R., Artz, Andrew, Thirman, Michael J., Moliterno, Alison, Ji, Peng, Levine, Ross L., Godley, Lucy A., Steidl, Ulrich, Bieker, James J., List, Alan F., Saunthararajah, Yogen, He, Chuan, Verma, Amit, Wickrema, Amittha
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697164/
https://ncbi.nlm.nih.gov/pubmed/30944118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1138
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados