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Methyl-Based NMR Spectroscopy Methods for Uncovering Structural Dynamics in Large Proteins and Protein Complexes

NMR spectroscopy is particularly adept at site-specifically monitoring dynamic processes in proteins, such as protein folding, domain movements, ligand binding, and side-chain rotations. By coupling the favorable spectroscopic properties of highly dynamic side-chain methyl groups with transverse-rel...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Boswell, Zachary K., Latham, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697110/
https://ncbi.nlm.nih.gov/pubmed/30336000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00953
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