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Clinical and immunological control of experimental autoimmune encephalomyelitis by tolerogenic dendritic cells loaded with MOG-encoding mRNA

BACKGROUND: Although effective in reducing relapse rate and delaying progression, current therapies for multiple sclerosis (MS) do not completely halt disease progression. T cell autoimmunity to myelin antigens is considered one of the main mechanisms driving MS. It is characterized by autoreactivit...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Derdelinckx, Judith, Mansilla, María José, De Laere, Maxime, Lee, Wai-Ping, Navarro-Barriuso, Juan, Wens, Inez, Nkansah, Irene, Daans, Jasmijn, De Reu, Hans, Jolanta Keliris, Aneta, Van Audekerke, Johan, Vanreusel, Verdi, Pieters, Zoë, Van der Linden, Annemie, Verhoye, Marleen, Molenberghs, Geert, Hens, Niel, Goossens, Herman, Willekens, Barbara, Cras, Patrick, Ponsaerts, Peter, Berneman, Zwi N., Martínez-Cáceres, Eva María, Cools, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696692/
https://ncbi.nlm.nih.gov/pubmed/31416452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1541-1
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