The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is characterized by dopaminergic neuronal loss in the substantia nigra pars compacta and intracellular inclusions called Lewy bodies (LB). During the course of disease, misfolded α-synuclein, the major constituent of LB, spreads to different regions of the brain...

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Enregistré dans:
Détails bibliographiques
Publié dans:Transl Neurodegener
Auteurs principaux: Pang, Shirley Yin-Yu, Ho, Philip Wing-Lok, Liu, Hui-Fang, Leung, Chi-Ting, Li, Lingfei, Chang, Eunice Eun Seo, Ramsden, David Boyer, Ho, Shu-Leong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696688/
https://ncbi.nlm.nih.gov/pubmed/31428316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-019-0165-9
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