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The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease
BACKGROUND: Parkinson’s disease (PD) is characterized by dopaminergic neuronal loss in the substantia nigra pars compacta and intracellular inclusions called Lewy bodies (LB). During the course of disease, misfolded α-synuclein, the major constituent of LB, spreads to different regions of the brain...
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| Pubblicato in: | Transl Neurodegener |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6696688/ https://ncbi.nlm.nih.gov/pubmed/31428316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-019-0165-9 |
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