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Revisiting the Role of LXRs in PUFA Metabolism and Phospholipid Homeostasis
Liver X receptors (LXRs) play a pivotal role in fatty acid (FA) metabolism. So far, the lipogenic consequences of in vivo LXR activation, as characterized by a major hepatic steatosis, has constituted a limitation to the clinical development of pharmacological LXR agonists. However, recent studies p...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6696407/ https://ncbi.nlm.nih.gov/pubmed/31382500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153787 |
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