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Strategies to Increase On-Target and Reduce Off-Target Effects of the CRISPR/Cas9 System in Plants

The CRISPR/Cas9 system (clustered regularly interspaced short palindromic repeat-associated protein 9) is a powerful genome-editing tool in animals, plants, and humans. This system has some advantages, such as a high on-target mutation rate (targeting efficiency), less cost, simplicity, and high-eff...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Hajiahmadi, Zahra, Movahedi, Ali, Wei, Hui, Li, Dawei, Orooji, Yasin, Ruan, Honghua, Zhuge, Qiang
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696359/
https://ncbi.nlm.nih.gov/pubmed/31366028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153719
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