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Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells

Accumulation of amyloid-β (Aβ), which results in the formation of senile plaques that cause oxidative damage and neuronal cell death, has been accepted as the major pathological mechanism of Alzheimer’s disease (AD). Hence, inhibition of Aβ-induced oxidative damage and neuronal cell apoptosis repres...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Liu, Meichen, Bai, Xueyuan, Yu, Shiting, Zhao, Wenxue, Qiao, Juhui, Liu, Ying, Zhao, Daqing, Wang, Jiawen, Wang, Siming
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696356/
https://ncbi.nlm.nih.gov/pubmed/31344860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152687
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