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Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells

Accumulation of amyloid-β (Aβ), which results in the formation of senile plaques that cause oxidative damage and neuronal cell death, has been accepted as the major pathological mechanism of Alzheimer’s disease (AD). Hence, inhibition of Aβ-induced oxidative damage and neuronal cell apoptosis repres...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Liu, Meichen, Bai, Xueyuan, Yu, Shiting, Zhao, Wenxue, Qiao, Juhui, Liu, Ying, Zhao, Daqing, Wang, Jiawen, Wang, Siming
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696356/
https://ncbi.nlm.nih.gov/pubmed/31344860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152687
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