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Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells

Accumulation of amyloid-β (Aβ), which results in the formation of senile plaques that cause oxidative damage and neuronal cell death, has been accepted as the major pathological mechanism of Alzheimer’s disease (AD). Hence, inhibition of Aβ-induced oxidative damage and neuronal cell apoptosis repres...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Liu, Meichen, Bai, Xueyuan, Yu, Shiting, Zhao, Wenxue, Qiao, Juhui, Liu, Ying, Zhao, Daqing, Wang, Jiawen, Wang, Siming
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696356/
https://ncbi.nlm.nih.gov/pubmed/31344860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152687
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