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Additive Pharmacological Interaction between Cisplatin (CDDP) and Histone Deacetylase Inhibitors (HDIs) in MDA-MB-231 Triple Negative Breast Cancer (TNBC) Cells with Altered Notch1 Activity—An Isobolographic Analysis

The aim of this study was to investigate the influence of the Notch1 activity level on the pharmacological interaction between cisplatin (CDDP) and two histone deacetylase inhibitors (HDIs)—valproic acid (VPA) and vorinostat (SAHA) in the triple negative breast cancer (TNBC) cells. Stable breast can...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Wawruszak, Anna, Luszczki, Jarogniew J., Kalafut, Joanna, Okla, Karolina, Halasa, Marta, Rivero-Muller, Adolfo, Stepulak, Andrzej
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696008/
https://ncbi.nlm.nih.gov/pubmed/31357442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153663
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