Additive Pharmacological Interaction between Cisplatin (CDDP) and Histone Deacetylase Inhibitors (HDIs) in MDA-MB-231 Triple Negative Breast Cancer (TNBC) Cells with Altered Notch1 Activity—An Isobolographic Analysis

The aim of this study was to investigate the influence of the Notch1 activity level on the pharmacological interaction between cisplatin (CDDP) and two histone deacetylase inhibitors (HDIs)—valproic acid (VPA) and vorinostat (SAHA) in the triple negative breast cancer (TNBC) cells. Stable breast can...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wawruszak, Anna, Luszczki, Jarogniew J., Kalafut, Joanna, Okla, Karolina, Halasa, Marta, Rivero-Muller, Adolfo, Stepulak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696008/
https://ncbi.nlm.nih.gov/pubmed/31357442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153663
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