Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues

Neuronal α4β2 nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels (LGIC) that have been implicated in nicotine addiction, reward, cognition, pain disorders, anxiety, and depression. Nicotine has been widely used as a template for the synthesis of ligands that prefer α4β2 nAChRs...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Gonzalez-Gutierrez, Juan Pablo, Hodar, Martin, Viscarra, Franco, Paillali, Pablo, Guerra-Díaz, Nicolás, Pessoa-Mahana, Hernán, Hernández-Morantes, Juan José, Pérez-Sánchez, Horacio, Bermúdez, Isabel, Reyes-Parada, Miguel, Iturriaga-Vásquez, Patricio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695845/
https://ncbi.nlm.nih.gov/pubmed/31344816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152684
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados