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Enhanced Nanoencapsulation of Sepiapterin within PEG-PCL Nanoparticles by Complexation with Triacetyl-Beta Cyclodextrin

In this work, we aimed to improve the encapsulation efficiency of sepiapterin (SP), the natural precursor of the essential cofactor tetrahydrobiopterin (BH4) that displays mild water-solubility and a short biological half-life, within methoxy-poly(ethylene-glycol)-poly(epsilon-caprolactone)(mPEG-PCL...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kuplennik, Nataliya, Sosnik, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695667/
https://ncbi.nlm.nih.gov/pubmed/31357400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152715
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