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Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles

BACKGROUND: Curcumin (CUR) has been linked with antioxidant, anti-inflammatory, antimicrobial, anti amyloid, and antitumor effects, but its application is limited because of its low aqueous solubility and poor oral bioavailability. METHODS: To improve its bioavailability and water solubility, we syn...

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Autors principals: Feng, Runliang, Song, Zhimei, Zhai, Guangxi
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414087/
https://ncbi.nlm.nih.gov/pubmed/22888245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S33607
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