Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2

Hyperaldosteronism alters cardiac function, inducing adverse left ventricle (LV) remodeling either via increased fibrosis deposition, mitochondrial dysfunction, or both. These harmful effects are due, at least in part, to the activation of the G protein-coupled receptor kinase 2 (GRK2). In this cont...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Cannavo, Alessandro, Marzano, Federica, Elia, Andrea, Liccardo, Daniela, Bencivenga, Leonardo, Gambino, Giuseppina, Perna, Claudia, Rapacciuolo, Antonio, Cittadini, Antonio, Ferrara, Nicola, Paolocci, Nazareno, Koch, Walter J., Rengo, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695474/
https://ncbi.nlm.nih.gov/pubmed/31447681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00888
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