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Alternate subunit assembly diversifies the function of a bacterial toxin

Bacterial toxins with an AB(5) architecture consist of an active (A) subunit inserted into a ring-like platform comprised of five delivery (B) subunits. Salmonella Typhi, the cause of typhoid fever, produces an unusual A(2)B(5) toxin known as typhoid toxin. Here, we report that upon infection of hum...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Fowler, Casey C., Stack, Gabrielle, Jiao, Xuyao, Lara-Tejero, Maria, Galán, Jorge E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695444/
https://ncbi.nlm.nih.gov/pubmed/31417089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11592-0
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