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Replication-Defective West Nile Virus with NS1 Deletion as a New Vaccine Platform for Flavivirus
We previously produced a replication-defective West Nile virus (WNV) lacking NS1 (WNV-ΔNS1) that could propagate at low levels (10(5) infectious units [IU]/ml) in a 293T cell line expressing wild-type (WT) NS1. This finding indicates the potential of developing WNV-ΔNS1 as a noninfectious vaccine. T...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6694808/ https://ncbi.nlm.nih.gov/pubmed/31189715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00720-19 |
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