Synthesis of Dextran–Phenoxodiol and Evaluation of Its Physical Stability and Biological Activity

Phenoxodiol, an isoflavene anti-tumor agent, was conjugated on the polysaccharide dextran using immobilized laccase as biocatalyst. The success of the enzymatic conjugation was determined by UV-vis spectrophotometry and its functionalization degree was assessed by (1)H NMR and was found to be 3.25 m...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Yee, Eugene M. H., Cirillo, Giuseppe, Brandl, Miriam B., Black, David StC, Vittorio, Orazio, Kumar, Naresh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694440/
https://ncbi.nlm.nih.gov/pubmed/31440502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00183
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