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Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

Formation of blood vessels, or angiogenesis, is crucial to cancer progression. Thus, inhibiting angiogenesis can limit the growth and spread of tumors. The natural polyphenol catechin has moderate anti-tumor activity and interacts with copper, which is essential for angiogenesis. Catechin is easily...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Yee, Eugene M. H., Brandl, Miriam B., Pasquier, Eddy, Cirillo, Giuseppe, Kimpton, Kathleen, Kavallaris, Maria, Kumar, Naresh, Vittorio, Orazio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550437/
https://ncbi.nlm.nih.gov/pubmed/28794411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07452-w
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