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Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

Formation of blood vessels, or angiogenesis, is crucial to cancer progression. Thus, inhibiting angiogenesis can limit the growth and spread of tumors. The natural polyphenol catechin has moderate anti-tumor activity and interacts with copper, which is essential for angiogenesis. Catechin is easily...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yee, Eugene M. H., Brandl, Miriam B., Pasquier, Eddy, Cirillo, Giuseppe, Kimpton, Kathleen, Kavallaris, Maria, Kumar, Naresh, Vittorio, Orazio
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550437/
https://ncbi.nlm.nih.gov/pubmed/28794411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07452-w
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