Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice

Brain-derived neurotrophic factor (BDNF) is a key player in synaptic plasticity, and consequently, learning and memory. Because of its fundamental role in numerous neurological functions in the central nervous system, BDNF has utility as a biomarker and drug target for neurodegenerative and neuropsy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fukuchi, Mamoru, Okuno, Yui, Nakayama, Hironori, Nakano, Aoi, Mori, Hisashi, Mitazaki, Satoru, Nakano, Yuka, Toume, Kazufumi, Jo, Michiko, Takasaki, Ichiro, Watanabe, Kazuki, Shibahara, Naotoshi, Komatsu, Katsuko, Tabuchi, Akiko, Tsuda, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694194/
https://ncbi.nlm.nih.gov/pubmed/31413298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48361-4
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