Class I Histone Deacetylase-mediated Repression of the Proximal Promoter of the Activity-regulated Cytoskeleton-associated Protein Gene Regulates Its Response to Brain-derived Neurotrophic Factor

We examined the transcriptional regulation of the activity-regulated cytoskeleton-associated protein gene (Arc), focusing on BDNF-induced Arc expression in cultured rat cortical cells. Although the synaptic activity-responsive element (SARE), located −7 kbp upstream of the Arc transcription start si...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fukuchi, Mamoru, Nakashima, Fukumi, Tabuchi, Akiko, Shimotori, Masataka, Tatsumi, Saori, Okuno, Hiroyuki, Bito, Haruhiko, Tsuda, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358108/
https://ncbi.nlm.nih.gov/pubmed/25623071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.617258
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