Class I Histone Deacetylase-mediated Repression of the Proximal Promoter of the Activity-regulated Cytoskeleton-associated Protein Gene Regulates Its Response to Brain-derived Neurotrophic Factor

We examined the transcriptional regulation of the activity-regulated cytoskeleton-associated protein gene (Arc), focusing on BDNF-induced Arc expression in cultured rat cortical cells. Although the synaptic activity-responsive element (SARE), located −7 kbp upstream of the Arc transcription start si...

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Vydáno v:J Biol Chem
Hlavní autoři: Fukuchi, Mamoru, Nakashima, Fukumi, Tabuchi, Akiko, Shimotori, Masataka, Tatsumi, Saori, Okuno, Hiroyuki, Bito, Haruhiko, Tsuda, Masaaki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358108/
https://ncbi.nlm.nih.gov/pubmed/25623071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.617258
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