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Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

Breast cancer stem cells (BCSCs) are unique in their ability to undergo unlimited self-renewal, an essential process in breast cancer recurrence following metastatic dormancy. Emergent metastatic lesions were subjected to microarray analysis, which identified 6-phosphofructo-2-kinase/fructose-2,6-bi...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: La Belle Flynn, Alyssa, Calhoun, Benjamin C., Sharma, Arishya, Chang, Jenny C., Almasan, Alexandru, Schiemann, William P.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694140/
https://ncbi.nlm.nih.gov/pubmed/31413316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11640-9
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