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PIM1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation

BACKGROUND: Interleukin-6 (IL-6) has been demonstrated to be a critical factor for breast cancer malignancy. However, the molecular mechanisms by which IL-6 induce breast cancer cells epithelial–mesenchymal-transition (EMT) and stemness remain elusive. METHODS: Breast cancer cell lines T47D and MCF7...

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Detalhes bibliográficos
Publicado no:Breast Cancer
Main Authors: Gao, Xueqiang, Liu, Xiangping, Lu, Yangyong, Wang, Yu, Cao, Weihong, Liu, Xiaoyi, Hu, Haiyan, Wang, Haibo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694096/
https://ncbi.nlm.nih.gov/pubmed/30989585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12282-019-00966-3
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