Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor

Wilms’ tumor is the most common type of childhood kidney cancer. To improve risk stratification and identify novel therapeutic targets for patients with Wilms’ tumor, we used high-resolution mass spectrometry proteomics to identify urine tumor markers associated with Wilms’ tumor relapse. We determi...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ortiz, Michael V., Ahmed, Saima, Burns, Melissa, Henssen, Anton G., Hollmann, Travis J., MacArthur, Ian, Gunasekera, Shehana, Gaewsky, Lyvia, Bradwin, Gary, Ryan, Jeremy, Letai, Anthony, He, Ying, Naranjo, Arlene, Chi, Yueh-Yun, LaQuaglia, Michael, Heaton, Todd, Cifani, Paolo, Dome, Jeffrey S., Gadd, Samantha, Perlman, Elizabeth, Mullen, Elizabeth, Steen, Hanno, Kentsis, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693841/
https://ncbi.nlm.nih.gov/pubmed/31391345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127098
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