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Prohibitin promotes dedifferentiation and is a potential therapeutic target in neuroblastoma
Gain of the long arm of chromosome 17 (17q) is a cytogenetic hallmark of high-risk neuroblastoma, yet its contribution to neuroblastoma pathogenesis remains incompletely understood. Combining whole-genome and RNA sequencing of neuroblastomas, we identified the prohibitin (PHB) gene as highly express...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6542629/ https://ncbi.nlm.nih.gov/pubmed/30998507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127130 |
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