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Augmentation of IFN-γ(+) CD8(+) T cell responses correlates with survival of HCC patients on sorafenib therapy
BACKGROUND: Sorafenib has been shown to reduce the extent of immunosuppression in patients with hepatocellular carcinoma (HCC). The rationale of this investigation was to identify biomarkers that can predict treatment efficacy of sorafenib in HCC patients and to unravel the mechanism by which sorafe...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693832/ https://ncbi.nlm.nih.gov/pubmed/31391334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130116 |
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