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High immunosuppressive burden in cancer patients: a major hurdle for cancer immunotherapy

A bottleneck for immunotherapy of cancer is the immunosuppressive microenvironment in which the tumor cells are located. Regardless of the fact that large numbers of tumor-specific T cells can be generated in patients by active immunization or adoptive transfer, these T cells do not readily translat...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Kalathil, Suresh Gopi, Thanavala, Yasmin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714319/
https://ncbi.nlm.nih.gov/pubmed/26910314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1810-0
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