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Niclosamide repurposed for the treatment of inflammatory airway disease

Inflammatory airway diseases, such as asthma, cystic fibrosis (CF), and chronic obstructive pulmonary disease (COPD), are characterized by mucus hypersecretion and airway plugging. In both CF and asthma, enhanced expression of the Ca(2+)-activated Cl(–) channel TMEM16A is detected in mucus-producing...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Cabrita, Inês, Benedetto, Roberta, Schreiber, Rainer, Kunzelmann, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693830/
https://ncbi.nlm.nih.gov/pubmed/31391337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128414
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