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Niclosamide repurposed for the treatment of inflammatory airway disease
Inflammatory airway diseases, such as asthma, cystic fibrosis (CF), and chronic obstructive pulmonary disease (COPD), are characterized by mucus hypersecretion and airway plugging. In both CF and asthma, enhanced expression of the Ca(2+)-activated Cl(–) channel TMEM16A is detected in mucus-producing...
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| Pubblicato in: | JCI Insight |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693830/ https://ncbi.nlm.nih.gov/pubmed/31391337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128414 |
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