Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation

Several studies have shown that dysfunction of macroautophagy/autophagy is associated with many human diseases, including neurodegenerative disease and cancer. To explore the molecular mechanisms of autophagy, we performed a cell-based functional screening with SH-SY5Y cells stably expressing GFP-LC...

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Veröffentlicht in:Autophagy
Hauptverfasser: Shin, Ji Hyun, Park, So Jung, Jo, Doo Sin, Park, Na Yeon, Kim, Joon Bum, Bae, Ji-Eun, Jo, Yoon Kyung, Hwang, Jung Jin, Lee, Jin-A, Jo, Dong-Gyu, Kim, Jin Cheon, Jung, Yong Keun, Koh, Jae-Young, Cho, Dong-Hyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693468/
https://ncbi.nlm.nih.gov/pubmed/30821607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1586249
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