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A TRIM32-AMBRA1-ULK1 complex initiates the autophagy response in atrophic muscle cells

The Ser/Thr protein kinase ULK1 is an upstream macroautophagy/autophagy regulator that is rapidly activated to ensure a proper adaptive response to stress conditions. Signaling pathways modulating ULK1 activity have been extensively characterized in response to nutrient/energy shortage, which mainly...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Di Rienzo, Martina, Piacentini, Mauro, Fimia, Gian Maria
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693449/
https://ncbi.nlm.nih.gov/pubmed/31234693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1635385
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