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Alteration of Bile Acid and Cholesterol Biosynthesis and Transport by Perfluorononanoic Acid (PFNA) in Mice

Perfluorochemicals produce hepatotoxic effects via activation of peroxisome proliferator-activated receptor alpha (PPARα) and constitutive androstane receptor (CAR) nuclear receptors in animals. Bile formation is one major liver function. But it remains unknown whether perfluorochemicals alter metab...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Zhang, Yue, Zhang, Youcai, Klaassen, Curtis D, Cheng, Xingguo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693384/
https://ncbi.nlm.nih.gov/pubmed/29112762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx237
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