Synthesis, Characterization, and Evaluation of Near-IR Boron Dipyrromethene Bioconjugates for Labeling of Adenocarcinomas by Selectively Targeting the Epidermal Growth Factor Receptor

A series of five boron dipyrromethene (BODIPY) bioconjugates containing an epidermal growth factor receptor (EGFR)-targeted pegylated LARLLT peptide and/or a glucose or biotin ethylene diamine group were synthesized, and the binding capability of the new conjugates to the extracellular domain of EGF...

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Veröffentlicht in:J Med Chem
Hauptverfasser: Kaufman, Nichole E. M., Meng, Qianli, Griffin, Kaitlin E., Singh, Sitanshu S., Dahal, Achyut, Zhou, Zehua, Fronczek, Frank R., Mathis, J. Michael, Jois, Seetharama D., Vicente, M. Graça H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693348/
https://ncbi.nlm.nih.gov/pubmed/30835998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b01746
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