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Mutation-Derived Neoantigens for Cancer Immunotherapy
Mutation-derived neoantigens distinguish tumor from normal cells. T cells can sense the HLA-presented mutations, recognize tumor cells as non-self and destroy them. Therapeutically, immunotherapy antibodies can increase the virulence of the immune system by increasing T-cell cytotoxicity targeted to...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693295/ https://ncbi.nlm.nih.gov/pubmed/31440245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01856 |
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